Taking CTEXLI | CTEXLI™ (chenodiol) | Official Patient Site

Orally

Take CTEXLI by mouth.
Swallow tablets whole.

3x per day

Take 1 CTEXLI tablet 3 times daily. Work with your doctor to find a schedule that works for you.

With or without food

CTEXLI can be taken with or without food.

What happens if a dose is missed?

Take CTEXLI as prescribed by your doctor. If you forget to take one of your scheduled CTEXLI tablets, skip the missed tablet. Take your next tablet at the normal, scheduled time.

Do not take 2 tablets at once.

It is important to keep taking CTEXLI, as stopping CTEXLI can cause toxins in the blood and urine to go back up.

Will CTEXLI affect or be affected by other medications?

Tell your health care provider about all the medications that you take, as CTEXLI may interact with other medicines. Do not take bile acid sequestering agents or aluminum-based antacids with CTEXLI. If you take coumarin, your doctor will need to monitor your prothrombin time while taking CTEXLI and may adjust your coumarin dose.

Talk to a health care provider to learn more about CTEXLI.

Resources are helpful when navigating your CTX journey

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CTEXLI has been shown to help reduce the production of harmful CTX toxins

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INDICATION

CTEXLI is indicated for the treatment of cerebrotendinous xanthomatosis (CTX) in adults.

IMPORTANT SAFETY INFORMATION

What are the possible side effects of CTEXLI?

Serious Side Effects—Hepatotoxicity (Liver Injury): You will need to undergo laboratory testing before starting and periodically while on treatment with CTEXLI to assess liver function. Changes in certain liver tests may occur during treatment and may be a sign of liver injury. People with preexisting liver disease or bile duct abnormalities may be at higher risk for liver injury during treatment. Stop taking CTEXLI immediately and tell your healthcare provider right away if you get any signs or symptoms of liver problems, including:
- Stomach (abdomen) pain
- Bruising
- Dark-colored urine
- Feeling tired (fatigue)
- Bleeding
- Yellowing of the skin and eyes
- Nausea
- Itching
Most Common Side Effects: Diarrhea, headache, stomach pain, constipation, high blood pressure, muscular weakness, and upper respiratory tract infection.

Tell your healthcare provider about all the medications that you take, as CTEXLI may interact with other medicines. Do not take bile acid sequestering agents or aluminum-based antacids with CTEXLI. If you take coumarin, your doctor will need to monitor your prothrombin time (PT) while taking CTEXLI and may adjust your coumarin dose.

Your healthcare provider may temporarily or permanently stop treatment if you have certain side effects.

CTEXLI is taken by mouth three (3) times each day and can be taken with or without food. Swallow tablets whole.

These are not all the possible side effects of CTEXLI. For more information, ask your healthcare provider or pharmacist. Tell your doctor if you have any side effect that bothers you or that does not go away.

You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Mirum Pharmaceuticals at 1-855-MRM-4YOU (1-855-676-4968).

Please see accompanying full Prescribing Information.

INDICATION

CTEXLI is indicated for the treatment of cerebrotendinous xanthomatosis (CTX) in adults.

IMPORTANT SAFETY INFORMATION

What are the possible side effects of CTEXLI?

Serious Side Effects—Hepatotoxicity (Liver Injury): You will need to undergo laboratory testing before starting and periodically while on treatment with CTEXLI to assess liver function. Changes in certain liver tests may occur during treatment and may be a sign of liver injury. People with preexisting liver disease or bile duct abnormalities may be at higher risk for liver injury during treatment. Stop taking CTEXLI immediately and tell your healthcare provider right away if you get any signs or symptoms of liver problems, including:
- Stomach (abdomen) pain
- Bruising
- Dark-colored urine
- Feeling tired (fatigue)
- Bleeding
- Yellowing of the skin and eyes
- Nausea
- Itching
Most Common Side Effects: Diarrhea, headache, stomach pain, constipation, high blood pressure, muscular weakness, and upper respiratory tract infection.

Tell your healthcare provider about all the medications that you take, as CTEXLI may interact with other medicines. Do not take bile acid sequestering agents or aluminum-based antacids with CTEXLI. If you take coumarin, your doctor will need to monitor your prothrombin time (PT) while taking CTEXLI and may adjust your coumarin dose.

Your healthcare provider may temporarily or permanently stop treatment if you have certain side effects.

CTEXLI is taken by mouth three (3) times each day and can be taken with or without food. Swallow tablets whole.

These are not all the possible side effects of CTEXLI. For more information, ask your healthcare provider or pharmacist. Tell your doctor if you have any side effect that bothers you or that does not go away.

You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Mirum Pharmaceuticals at 1-855-MRM-4YOU (1-855-676-4968).

Please see accompanying full Prescribing Information.