Resources | CTEXLI™ (chenodiol) | Official Patient Site

Resources for living with CTX

CTX Alliance

The CTX Alliance is a patient organization solely dedicated to providing resources and support, and promoting CTX research for patients, families, and health care providers.

Visit the CTX Alliance

CTEXLI Brochure

To learn more about CTEXLI, download the brochure and talk to a health care provider.

Download the Brochure

Stay in the Know

Receive more information about CTEXLI as it becomes available.

Mirum Access Plus is available to support you

To learn more about Mirum Access Plus, contact us at 1-855-MRM-4YOU (1-855-676-4968) Monday through Friday, 8:00 am through 8:00 pm ET.

Talk to a health care provider to learn more about CTEXLI.

INDICATION

CTEXLI is indicated for the treatment of cerebrotendinous xanthomatosis (CTX) in adults.

IMPORTANT SAFETY INFORMATION

What are the possible side effects of CTEXLI?

Serious Side Effects—Hepatotoxicity (Liver Injury): You will need to undergo laboratory testing before starting and periodically while on treatment with CTEXLI to assess liver function. Changes in certain liver tests may occur during treatment and may be a sign of liver injury. People with preexisting liver disease or bile duct abnormalities may be at higher risk for liver injury during treatment. Stop taking CTEXLI immediately and tell your healthcare provider right away if you get any signs or symptoms of liver problems, including:
- Stomach (abdomen) pain
- Bruising
- Dark-colored urine
- Feeling tired (fatigue)
- Bleeding
- Yellowing of the skin and eyes
- Nausea
- Itching
Most Common Side Effects: Diarrhea, headache, stomach pain, constipation, high blood pressure, muscular weakness, and upper respiratory tract infection.

Tell your healthcare provider about all the medications that you take, as CTEXLI may interact with other medicines. Do not take bile acid sequestering agents or aluminum-based antacids with CTEXLI. If you take coumarin, your doctor will need to monitor your prothrombin time (PT) while taking CTEXLI and may adjust your coumarin dose.

Your healthcare provider may temporarily or permanently stop treatment if you have certain side effects.

CTEXLI is taken by mouth three (3) times each day and can be taken with or without food. Swallow tablets whole.

These are not all the possible side effects of CTEXLI. For more information, ask your healthcare provider or pharmacist. Tell your doctor if you have any side effect that bothers you or that does not go away.

You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Mirum Pharmaceuticals at 1-855-MRM-4YOU (1-855-676-4968).

Please see accompanying full Prescribing Information.